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Menciona que se ha investigado en afecciones como enfermedad inflamatoria intestinal y curacin de tejidos, pero que muchos ensayos se cancelaron sin resultados publicadosusada.org

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Before the company applied to the FDA for the drug to be approved for obesity, Knudsen and her colleagues 'developed a new methodology to show how [GLP-1] drugs exert their effect on the brain by working on the circumventricular organs and communicating further into the hypothalamus, among other effects.' This was designed to illustrate how GLP-1 worked in 'well- defined neurons in the hypothalamus, in the hindbrain, and in the reward centers.' Their rationale for developing the method was because 'It was very important to show that these medicines work on defined brain circuits and not ones that may be related to psychiatric or cardiovascular side effects, for example' (Nair

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Ileus occurs when the intestines cant move food or waste from the body and can cause complications, including intestinal perforation, tissue death, and abdominal infections

Hamdan A, Eastaugh J, Snygg J, Naidu J, Alhaj I